User blog comment:Roygbiv666/What are Splicers splicing?/@comment-24.247.176.141-20100815052117

Constant splicing messes up with the brain and thought processes. When you select a thug splicer in the help section of the menu, it's says more or less that these splicers have abused so much ADAM that they don't have the motor skills to hold a gun.