User blog comment:Beast of burden/Little Brothers and Big Mommas/@comment-6024608-20131018194609/@comment-16410636-20131018233137

interesting well i read that they did try to make little brothers im sure there was a eco log from tennanebaum but still if they were abandoned they would go ferral and where the little sisters wate until there dead the little brothers dont wate they make them dead, so all it takes is one tyrant asshole to relize he can use that.

little sisters can be used in the adopt/rescue/harvest options so u can get more ADAM out of it but the Little Brothers carry 40% ADAM from every corpse they devouerer so u can leave a banquet behind for the little devils so u can then harvest them or be given ADAM by the ones who see u as a freind (by rescuing the Big Momma). in each level im thinkng thers up to at least 3 little sisters but there is  singel Big Momma with 6 Little Brothers.(if u want to harvest them just let her die first.)