User blog comment:Mr. Youtube/Columbia and Rapture/@comment-2250991-20110902010911

Sorry, but as much thought you put into that theory, it's really no different from a hundred like it, which were debunked. It's been mentioned that BioShock Infinite might not have anything to do with Rapture, especially when it's creator, Ken Levine, mentions that the concept for the franchise is more in the direction of the Final Fantasy approach, where it has the same theme and archetypes, but it explores other destroyed utopias, rather than centering around just one. Even the TBA BioShock game for the Playstation Vita is said to be another different Utopia.

Andrew Ryan would never go that low to being a parasite in stealing anything from Columbia. He built Rapture for those like him to escape from a regulated government and religious censorship, even when his laws and paranoia of parasitic thieves and surface spies soon conflict his decisions to his citizens, which caused a war that not even pheromone mind-control could help balance. Columbia, like Rapture, is no paradise, either. It was built as a shining example of American patriotism to the world, despite that view being from one's xenophobic and racially bias views, which conflict with other citizens' views of their own patriotism, resulting in a war of factions. The only similarities are just that they're both failed utopias, and Columbia doesn't even look anything like Rapture, especially in the design.

Also, Plasmids work a lot differently from Vigors. Plasmids are just injected and permanently alter one's genetic code for that ability, only to refill those abilities with EVE. Vigors are temporary, and are drank to get those abilities again, not injected. And even though there's little info on where Vigors originated from, the ADAM used in Plasmids and Tonics comes from special Sea Slug-attached Little Sisters, which Columbia doesn't have anything like that, especially when there's no harvesting.