User blog comment:Willbachbakal/Singleplayer Enemies: Little Sister/@comment-75.36.137.232-20130909133507

Isnt this kind of defeating the role the Little Sister plays as something that gets protected (by Big Daddies or Player or maybe Splicers who have acquired their own). That caused different situations where the protector of whatever type needs to have maintaining the Little Sister as a Goal (including obtaining someone elses LS)  and to  take certain actions restricted in pursuit of that goal?

Perhaps have ones who instead of copying what SPlicers and other fighting type have, some may be manipulative or clever  setting their protector  onto whomever they are 'playing with' or leading you into an ambush or whatever. HAving a few Cute nasty little childs might be an interesting change  (especially in a period where their 'conditioning'  might not be to well maintained any more).

Complementary action which might be required would be the player having to bribe 'the little monsters' to get them to do what the player wants.