User blog comment:Pawn of Atlas/Important Discussion for Rapture Storyline page/@comment-75.36.142.227-20140329223049/@comment-75.36.138.211-20140331085755

Ryan was talking about Marketing using Little Sisters as an Icon (especially since they were now walking the streets 'gathering'). Before that (by Fontaine initially) they were warehoused and being used to generate that 20-30X as much as just the Seaslugs in aquariums (thats what Tenenbaum told Fontaine who then set up the orphanages to get all the little girls for hosts). Fontaine needed that much production to be able to make his fortune selling so much ADAM products to consumers.

I doubt Ryan would have discarded the little girl producers (or even shut down "orphanages"- changed their name but maybe tehrefore NOT take any new children) and dumped them on the street if the ADAM operation was dependant on them to keep people from rioting if they didnt get their ADAM 'fix'

Now the 'marketing' comment by Ryan - remember its talk ... - does that mean he is going to expand the business (why would he really want to that with the problems it was destabalizing the population and maybe already having shortages or needing it to fight Atlas ??  OR just cutting out the middleman and unneeded expenses from the existing business (using machines) ???

Again its all open to interpretation, and vague otherwise since they (audio diaries) dont constitute any hard narration spelling out things that actually happened.