User blog comment:D.Ryan/Episode 4/@comment-1595513-20100128043922

Alright, here goes. I'm gonna say Brute Splicer. The Big Sister needs to be close enough to inject the needle. I guess the Brute knows what's going to happen when she's getting close. He could easily break her arm. Anything thrown can be catched by the other. The Brute has a lot of health too, so when she's throwing fireballs, he could ram her.