User blog comment:Mr. Youtube/Columbia and Rapture/@comment-2250991-20110902010911/@comment-174.254.224.225-20130425235857

omg. ok plasmids were made from sea slugs. read the rapture history. cripples were bit by the sea slug and then could walk, they were then harvested and turned into adam. little girls are the only ones compatible with the actual slug. creating little sisters. they are in diff realities i believe. if it will explain later maybe vigors were created from sky slugs ahaha or something like that. rapture and columbia are most likely in diff realities. because. each light house is a diff universe. the light on the lighthouse is a start. each world. has a man. and that man created a city. now get this. there is most likely a reality were rapture and columbia exist together in the same world. but as for bioshock 1,2 and infinite they are in diff realities.