User blog comment:Androyd09/Blaster/@comment-74.15.6.70-20110209044624/@comment-3412492-20110211154707

Pretty much, although canon states that any Little Sister you see is invincible. And before you say "what's the difference?" infinite health implies they can be harmed but not beaten (and is a completely different subject to the incident where one broke her legs). So technically you are right Anon.