User blog comment:Dark Swarmlord/Infernus - The Judge's Plasmid/@comment-3412492-20110526112851/@comment-1330314-20110526171751

Hmmm...

Sofia Lamb and Fontaine, and so their respective factions, were both heretics to Ryan's ideals, Jack and Delta stood as heretics against the rest of the Splicers, and the latter comitted heresy against nature by splicing. Over time pretty much the entire population of Rapture also lost faith in Ryan and his principles and turned away from him, and then the entire city pretty much went to pot. Hope this works.