User blog comment:MegaScience/The Painting in the BioShock Infinite Gameplay/@comment-1401334-20101001203843

My theory is that Irrational may have used an actual portrait from that time period. Several of the paintings in the bar are actual historical paintings. For example, the painting in the corner (which you can only really see when DeWitt fires the shotgun at the bartender) is a version of this painting by N.C. Wyeth.