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For the Gene Tonics in BioShock, see BioShock Gene Tonics.

Gene Tonics are special serums made from processed ADAM that insert modified stem cells into the body, allowing for genetic modification and mutation, giving the user what some might call "super powers". In BioShock 2, the player as Subject Delta is able to choose from a vast selection of Tonics to equip. With Tonic Slot upgrades, the player can equip up to eighteen tonics. Tonics can be equipped and mixed in any order up to the maximum number. Most tonics are purchased at Gatherer's Gardens or found throughout the game, the rest can be earned by doing research. Tonics can be swapped at a Gene Bank. Gene Tonic bottles in BioShock 2 glow a bright blue color.

Main Game[]

Armored Shell[]

Effect: Reduces physical damage taken.
Location: Bought at Gatherer's Garden.
Price: 45

Armored Shell 2[]

Effect: Further reduces physical damage taken.
Location: Obtained by researching Brute Splicers to the maximum level.
Price: N/A

Arms Race[]

Effect: Able to find more ammo when looting bodies or containers.
Location: Obtained by researching Big Daddies to the maximum level.
Price: N/A

Booze Hound[]

Effect: Drinking alcohol restores a small amount of EVE, rather than draining it.
Location: Through a locked door at the beginning of the 'Journey to the Surface' ride in Ryan Amusements, or bought at a Gatherer's Garden.
Price: 40

Careful Hacker[]

Effect: The hacking needle moves slightly slower.
Location: Bought at Gatherer's Garden.
Price: 25

Careful Hacker 2[]

Effect: The hacking needle moves even slower.
Location: In Fontaine Futuristics behind coded door in Plasmid Demonstration area, or bought at a Gatherer's Garden.
Price: 50

Cure All[]

Effect: Health Stations also refill the player's EVE.
Location: Found in back room of Joe's Green Groceries in Siren Alley, or bought at a Gatherer's Garden.
Price: 40

Damage Research[]

Effect: Increases research damage bonuses.
Location: Found in a red wagon at the beginning of Fontaine Futuristics, or bought at a Gatherer's Garden.
Price: 45

Deadly Machines[]

Effect: Friendly Turrets and Security Bots deal more damage.
Location: Obtained by researching Security to the maximum level.
Price: N/A

Demanding Father[]

Effect: Little Sisters harvest bodies faster.
Location: Little Sister Gift after rescuing 8 Little Sisters.
Price: N/A

Drill Lurker[]

Effect: Quiets the player's footsteps, and increases damage from melee attacks on unaware opponents, especially with the Drill.
Location: Bought at Gatherer's Garden.
Price: 30

Drill Power[]

Effect: Increases damage dealt by the Drill.
Location: Just inside the El Dorado Lounge in Ryan Amusements, or bought at a Gatherer's Garden.
Price: 50

Drill Power 2[]

Effect: Further increases damage dealt by the Drill.
Location: In Fontaine Futuristics, in a room reachable through a hole on the second floor, or bought at a Gatherer's Garden.
Price: 75

Drill Specialist[]

Effect: Significantly decreases EVE cost of Plasmids, but limits weapon selection to the Drill, Hack Tool and Research Camera.
Location: In Dionysus Park, in the back room of the J. Fischer Gallery, or bought at a Gatherer's Garden.
Price: 75

Drill Vampire[]

Effect: Successful attacks with the Drill recharge the player's Health and EVE.
Location: Obtained by researching Big Sisters to the maximum level.
Price: N/A

Electric Flesh[]

Effect: Grants the user an immunity to electricity and increases electrical damage done.
Location: Bought at Gatherer's Garden.
Price: 35

Electrical Storm[]

Effect: Causes the user to emit a burst of electricity when struck by a melee attack.
Location: In the ladies' room of the Triton Theater in Dionysus Park, or bought at a Gatherer's Garden.
Price: 60

Elemental Sponge[]

Effect: User gains EVE when damaged by elemental attacks.
Location: Found in a prison cell on the far side of Cell Block B in Inner Persephone.
Price: N/A

Elemental Storm[]

Effect: Causes the user to emit a burst of fire, electricity or ice at random when struck by a melee attack.
Location: Obtained by researching Alpha Series to the maximum level.
Price: N/A

Elemental Vampire[]

Effect: Damaging enemies with a charged level 3 elemental Plasmid will recharge the user's Health.
Location: In Solitary Confinement in Cell Block North Quad of the Holding wing of Inner Persephone.
Price: N/A

EVE Expert[]

Effect: Increases EVE Hypo carry capacity by 1.
Location: In Dionysus Park in the lobby of Lamb's Garden behind a broken door, or bought at a Gatherer's Garden.
Price: 50

EVE Link[]

Effect: First Aid Kits also give a small amount of EVE.
Location: Bought at Gatherer's Garden.
Price: 30

EVE Saver[]

Effect: Reduces EVE consumption of all Plasmids.
Location: Bought at Gatherer's Garden.
Price: 50

EVE Saver 2[]

Effect: Further reduces EVE consumption of all Plasmids.
Location: Bought at Gatherer's Garden.
Price: 75

Extended Reel[]

Effect: Increases the time the user can spend researching an enemy.
Location: In Dionysus Park in the projector room on the top floor of the Triton Theater, or bought at a Gatherer's Garden.
Price: 35

Extra Nutrition[]

Effect: Gain a small increase in health from consumables.
Location: Bought at Gatherer's Garden.
Price: 20

EZ-Hack[]

Effect: Hacking success zones become a little larger.
Location: Bought at Gatherer's Garden.
Price: 55

Fire Storm[]

Effect: Causes the user to emit a burst of fire when struck by a melee attack.
Location: Found in Pauper's Drop right before the door to the rooftop walkway, or bought at a Gatherer's Garden.
Price: 35

Fountain of Youth[]

Effect: User slowly regenerates Health and EVE when in contact with a body of water.
Location: Obtained by researching Spider Splicers to the maximum level.
Price: N/A

Freezing Drill[]

Effect: Increases the duration for which enemies are frozen and gives the Drill a chance to freeze the enemy upon impact.
Location: On a vent shrine in The Sinclair Deluxe in Pauper's Drop, or bought at a Gatherer's Garden.
Price: 60

Hacker's Delight[]

Effect: Some Health and EVE are gained after a successful hack.
Location: Located in a small hole in the wall, accessed by a wooden plank extending off the roof of the Fishbowl Diner in Pauper's Drop, or bought at a Gatherer's Garden.
Price: 40

Hacker's Delight 2[]

Effect: More Health and EVE are gained after a successful hack.
Location: Under Daniel Wales’ apartment in the dark room with two Machine Gun Turrets in Siren Alley, or bought at a Gatherer's Garden.
Price: 60

Handyman[]

Effect: Allows the user to repair damaged Security Bots and Turrets, also assigning them a random name.
Location: In Siren Alley on the bottom floor of a locked shop in the center of Little Eden Plaza, or purchased at a Gatherer's Garden.
Price: 65

Hardy Machines[]

Effect: Friendly Turrets and Security Bots have more health.
Location: In Dionysus Park in front of the Safe in the back room of Imago Fine Arts, or bought at a Gatherer's Garden.
Price: 50

Headhunter[]

Effect: The player's headshots do more damage.
Location: Bought at Gatherer's Garden.
Price: 50

Hurried Hacker[]

Effect: Landing in a blue bonus zone completes a hack instantly.
Location: Bought at Gatherer's Garden.
Price: 45

Ice Storm[]

Effect: Causes the user to emit a burst of ice when struck by a melee attack.
Location: Bought at Gatherer's Garden.
Price: 35

Keen Observer[]

Effect: Increases the research score gained by damaging enemies.
Location: In Pauper's Drop on a table with a microscope near Grace Holloway's room, or bought at a Gatherer's Garden.
Price: 40

Keen Observer 2[]

Effect: Further increases the research score gained by damaging enemies.
Location: Bought at Gatherer's Garden.
Price: 50

Machine Buster[]

Effect: User deals more damage against Turrets, Security Cameras and Security Bots.
Location: Bought at Gatherer's Garden.
Price: 45

Medical Expert[]

Effect: Increases First Aid Kit carry capacity by 1.
Location: Bought at Gatherer's Garden.
Price: 25

Natural Camouflage[]

Effect: Grants invisibility when standing still for a period of time.
Location: Obtained by researching Houdini Splicers to the maximum level.
Price: N/A

Proud Parent[]

Effect: Little Sisters give the player an extra 20 ADAM after gathering.
Location: Little Sister Gift after rescuing 4 Little Sisters.
Price: N/A

Quik-Hack[]

Effect: Hacking has fewer stages.
Location: Bought at Gatherer's Garden.
Price: 45

Scrounger[]

Effect: Allows the player to search corpses twice for different loot.
Location: Obtained by researching Thuggish Splicers to the maximum level.
Price: N/A

Security Evasion[]

Effect: Security Cameras and Turrets take two seconds longer to track the player.
Location: Bought at Gatherer's Garden.
Price: 45

Short Circuit[]

Effect: Security is disabled for longer when hit with electricity.
Location: Bought at Gatherer's Garden.
Price: 35

Short Circuit 2[]

Effect: Security is disabled permanently when hit with electricity.
Location: Bought at Gatherer's Garden.
Price: 65

Shorten Alarms[]

Effect: Reduces the length of hostile security alarms by 20 seconds.
Location: In Pauper's Drop on a cabinet in the northernmost room on the roofs of Town Square, or bought at a Gatherer's Garden.
Price: 30

Shorten Alarms 2[]

Effect: Reduces the length of hostile security alarms by 40 seconds.
Location: Bought at Gatherer's Garden.
Price: 50

Sports Boost[]

Effect: Slightly increases movement speed
Location: At the beginning of Ryan Amusements, under the sign "Memorial Museum", or bought at a Gatherer's Garden.
Price: 40

Thrifty Hacker[]

Effect: Hacked vending prices are even cheaper.
Location: Obtained by researching Leadhead Splicers to the maximum level.
Price: N/A

Vending Expert[]

Effect: Provides a slight reduction to prices in vending machines.
Location: Downstairs in a flooded section of Siren Alley, or bought at a Gatherer's Garden.
Price: 75

Vending Expert 2[]

Effect: Provides a substantial reduction to prices in vending machines.
Location: Reward for "following" the Unstable Teleportation Plasmid in Fontaine Futuristics, or bought at a Gatherer's Garden.
Price: 90

Walking Inferno[]

Effect: Boosts the effects of the user's fire-based attacks while providing a resistance to fire damage.
Location: Bought at Gatherer's Garden.
Price: 40

Minerva's Den Only[]

Main article: Minerva's Den

Drill Dash[]

Effect: Unlocks the Drill Dash ability when equipped.
Location: Found in the Security Bot showroom right after the entrance of McClendon Robotics, in Minerva's Den, or bought in Gatherer's Gardens.
Price: 75

Master Protector[]

Effect: Increases harvest times for any Little Sister the player's chaperoning, thereby increasing the amount of ADAM they collect by 40.
Location: Free at any Gatherer's Garden only if the player obtained all stars in the The Protector Trials.
Price: Free

Mentioned Gene Tonics[]

Animal Magnetism[]

Effect: Increases the user's charisma and seductory prowess (if male).
Location: N/A
Price: Unknown

Anti-TB[]

Effect: Immunizes the user against tuberculosis.
Location: N/A
Price: Unknown

Brain Boost[]

Effect: Improves the user's thinking capabilities.
Location: N/A
Price: Unknown

Hemingway's Helper[]

N/A Effect: Cures writer's block and makes the user a better writer.
Location: N/A
Price: Unknown, but included with the Sinclair Solution's Tester Pack.

Slim-Down[]

Effect: Sheds the user's excess fat.
Location: N/A
Price: Unknown

ReJuvena[]

Effect: Tightens skin to reduce wrinkles.
Location: N/A
Price: Unknown

Removed Gene Tonics[]

EVE Auto Hack[]

Piercing Damage Over Time[]

Staggering Blow[]

Gatherer Harvest Bonus[]

Handyman 2[]

Freezing Drill 2[]

Medical Expert 2[]

Behind the Scenes[]

  • In BioShock 2's game files, there is a TonicBasicTraining video. When played, it plays a short version of the Enrage Plasmid's video, except "Tonics" is layered over the "Plasmids" at the start, and it seems to state it is a "PLACEHOLDER" for Tonic use videos. Considering this, one may assume the developers were planning on making the same Plasmid introductory videos for Tonics. This can be seen at Ryan Amusements on a screen in the Hall of The Future. There's no sound and the "Tonics by Ryan Industries" sign does not appear.
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