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Physical Tonic
For the Gene Tonics in BioShock, see BioShock Gene Tonics.

Gene Tonics are special serums made from processed ADAM that insert modified stem cells into the body, allowing for genetic modification and mutation, giving the user what some might call "super powers". In BioShock 2, the player as Subject Delta is able to choose from a vast selection of Tonics to equip. With Tonic Slot upgrades, the player can equip up to eighteen tonics. Tonics can be equipped and mixed in any order up to the maximum number. Most tonics are purchased at Gatherer's Gardens or found throughout the game, the rest can be earned by doing research. Tonics can be swapped at a Gene Bank. Gene Tonic bottles in BioShock 2 glow a bright blue color.

Main Game[]

Armored Shell[]

Amor
Effect: Reduces physical damage taken.
Location: Bought at Gatherer's Garden.
Price: 45

Armored Shell 2[]

Armored Shell 2 Icon Effect: Further reduces physical damage taken.
Location: Obtained by researching Brute Splicers to the maximum level.
Price: N/A

Arms Race[]

Arms Race Effect: Able to find more ammo when looting bodies or containers.
Location: Obtained by researching Big Daddies to the maximum level.
Price: N/A

Booze Hound[]

Booze Hound Icon
Effect: Drinking alcohol restores a small amount of EVE, rather than draining it.
Location: Through a locked door at the beginning of the 'Journey to the Surface' ride in Ryan Amusements, or bought at a Gatherer's Garden.
Price: 40

Careful Hacker[]

Careful Hacker Effect: The hacking needle moves slightly slower.
Location: Bought at Gatherer's Garden.
Price: 25

Careful Hacker 2[]

Careful Hacker 2 Effect: The hacking needle moves even slower.
Location: In Fontaine Futuristics behind coded door in Plasmid Demonstration area, or bought at a Gatherer's Garden.
Price: 50

Cure All[]

Cure All (True)
Effect: Health Stations also refill the player's EVE.
Location: Found in back room of Joe's Green Groceries in Siren Alley, or bought at a Gatherer's Garden.
Price: 40

Damage Research[]

Damage Research
Effect: Increases research damage bonuses.
Location: Found in a red wagon at the beginning of Fontaine Futuristics, or bought at a Gatherer's Garden.
Price: 45

Deadly Machines[]

Deadly Machines Effect: Friendly Turrets and Security Bots deal more damage.
Location: Obtained by researching Security to the maximum level.
Price: N/A

Demanding Father[]

Demanding Father Effect: Little Sisters harvest bodies faster.
Location: Little Sister Gift after rescuing 8 Little Sisters.
Price: N/A

Drill Lurker[]

Clean drill lurker
Effect: Quiets the player's footsteps, and increases damage from melee attacks on unaware opponents, especially with the Drill.
Location: Bought at Gatherer's Garden.
Price: 30

Drill Power[]

Clean drill power
Effect: Increases damage dealt by the Drill.
Location: Just inside the El Dorado Lounge in Ryan Amusements, or bought at a Gatherer's Garden.
Price: 50

Drill Power 2[]

Clean drill power2
Effect: Further increases damage dealt by the Drill.
Location: In Fontaine Futuristics, in a room reachable through a hole on the second floor, or bought at a Gatherer's Garden.
Price: 75

Drill Specialist[]

Clean drill spec
Effect: Significantly decreases EVE cost of Plasmids, but limits weapon selection to the Drill, Hack Tool and Research Camera.
Location: In Dionysus Park, in the back room of the J. Fischer Gallery, or bought at a Gatherer's Garden.
Price: 75

Drill Vampire[]

Clean drill vampire
Effect: Successful attacks with the Drill recharge the player's Health and EVE.
Location: Obtained by researching Big Sisters to the maximum level.
Price: N/A

Electric Flesh[]

Field
Effect: Grants the user an immunity to electricity and increases electrical damage done.
Location: Bought at Gatherer's Garden.
Price: 35

Electrical Storm[]

Static
Effect: Causes the user to emit a burst of electricity when struck by a melee attack.
Location: In the ladies' room of the Triton Theater in Dionysus Park, or bought at a Gatherer's Garden.
Price: 60

Elemental Sponge[]

Elemental Sponge Effect: User gains EVE when damaged by elemental attacks.
Location: Found in a prison cell on the far side of Cell Block B in Inner Persephone.
Price: N/A

Elemental Storm[]

Elemental Storm Effect: Causes the user to emit a burst of fire, electricity or ice at random when struck by a melee attack.
Location: Obtained by researching Alpha Series to the maximum level.
Price: N/A

Elemental Vampire[]

Elemental Vampire Effect: Damaging enemies with a charged level 3 elemental Plasmid will recharge the user's Health.
Location: In Solitary Confinement in Cell Block North Quad of the Holding wing of Inner Persephone.
Price: N/A

EVE Expert[]

EVE Expert Effect: Increases EVE Hypo carry capacity by 1.
Location: In Dionysus Park in the lobby of Lamb's Garden behind a broken door, or bought at a Gatherer's Garden.
Price: 50

EVE Link[]

39
Effect: First Aid Kits also give a small amount of EVE.
Location: Bought at Gatherer's Garden.
Price: 30

EVE Saver[]

EVE Saver Effect: Reduces EVE consumption of all Plasmids.
Location: Bought at Gatherer's Garden.
Price: 50

EVE Saver 2[]

EVE Saver 2 Effect: Further reduces EVE consumption of all Plasmids.
Location: Bought at Gatherer's Garden.
Price: 75

Extended Reel[]

Extended Reel Effect: Increases the time the user can spend researching an enemy.
Location: In Dionysus Park in the projector room on the top floor of the Triton Theater, or bought at a Gatherer's Garden.
Price: 35

Extra Nutrition[]

94 Effect: Gain a small increase in health from consumables.
Location: Bought at Gatherer's Garden.
Price: 20

EZ-Hack[]

EZ-Hack Effect: Hacking success zones become a little larger.
Location: Bought at Gatherer's Garden.
Price: 55

Fire Storm[]

Fire Storm Effect: Causes the user to emit a burst of fire when struck by a melee attack.
Location: Found in Pauper's Drop right before the door to the rooftop walkway, or bought at a Gatherer's Garden.
Price: 35

Fountain of Youth[]

Fountain of Youth Effect: User slowly regenerates Health and EVE when in contact with a body of water.
Location: Obtained by researching Spider Splicers to the maximum level.
Price: N/A

Freezing Drill[]

28
Effect: Increases the duration for which enemies are frozen and gives the Drill a chance to freeze the enemy upon impact.
Location: On a vent shrine in The Sinclair Deluxe in Pauper's Drop, or bought at a Gatherer's Garden.
Price: 60

Hacker's Delight[]

Hack
Effect: Some Health and EVE are gained after a successful hack.
Location: Located in a small hole in the wall, accessed by a wooden plank extending off the roof of the Fishbowl Diner in Pauper's Drop, or bought at a Gatherer's Garden.
Price: 40

Hacker's Delight 2[]

Hacking Expert 2 Icon Effect: More Health and EVE are gained after a successful hack.
Location: Under Daniel Wales’ apartment in the dark room with two Machine Gun Turrets in Siren Alley, or bought at a Gatherer's Garden.
Price: 60

Handyman[]

Handyman 128px Effect: Allows the user to repair damaged Security Bots and Turrets, also assigning them a random name.
Location: In Siren Alley on the bottom floor of a locked shop in the center of Little Eden Plaza, or purchased at a Gatherer's Garden.
Price: 65

Hardy Machines[]

Hardy Machines Effect: Friendly Turrets and Security Bots have more health.
Location: In Dionysus Park in front of the Safe in the back room of Imago Fine Arts, or bought at a Gatherer's Garden.
Price: 50

Headhunter[]

Headhunter Effect: The player's headshots do more damage.
Location: Bought at Gatherer's Garden.
Price: 50

Hurried Hacker[]

Hurried Hacker Effect: Landing in a blue bonus zone completes a hack instantly.
Location: Bought at Gatherer's Garden.
Price: 45

Ice Storm[]

Ice Storm Effect: Causes the user to emit a burst of ice when struck by a melee attack.
Location: Bought at Gatherer's Garden.
Price: 35

Keen Observer[]

Keen Observer Effect: Increases the research score gained by damaging enemies.
Location: In Pauper's Drop on a table with a microscope near Grace Holloway's room, or bought at a Gatherer's Garden.
Price: 40

Keen Observer 2[]

Keen Observer 2 Effect: Further increases the research score gained by damaging enemies.
Location: Bought at Gatherer's Garden.
Price: 50

Machine Buster[]

Machine Buster Effect: User deals more damage against Turrets, Security Cameras and Security Bots.
Location: Bought at Gatherer's Garden.
Price: 45

Medical Expert[]

37
Effect: Increases First Aid Kit carry capacity by 1.
Location: Bought at Gatherer's Garden.
Price: 25

Natural Camouflage[]

53
Effect: Grants invisibility when standing still for a period of time.
Location: Obtained by researching Houdini Splicers to the maximum level.
Price: N/A

Proud Parent[]

Proud Parent Effect: Little Sisters give the player an extra 20 ADAM after gathering.
Location: Little Sister Gift after rescuing 4 Little Sisters.
Price: N/A

Quik-Hack[]

Quik-Hack Effect: Hacking has fewer stages.
Location: Bought at Gatherer's Garden.
Price: 45

Scrounger[]

33
Effect: Allows the player to search corpses twice for different loot.
Location: Obtained by researching Thuggish Splicers to the maximum level.
Price: N/A

Security Evasion[]

Security Evasion
Effect: Security Cameras and Turrets take two seconds longer to track the player.
Location: Bought at Gatherer's Garden.
Price: 45

Short Circuit[]

Short Circuit Effect: Security is disabled for longer when hit with electricity.
Location: Bought at Gatherer's Garden.
Price: 35

Short Circuit 2[]

Short Circuit 2 Effect: Security is disabled permanently when hit with electricity.
Location: Bought at Gatherer's Garden.
Price: 65

Shorten Alarms[]

25
Effect: Reduces the length of hostile security alarms by 20 seconds.
Location: In Pauper's Drop on a cabinet in the northernmost room on the roofs of Town Square, or bought at a Gatherer's Garden.
Price: 30

Shorten Alarms 2[]

Shorten Alarms 2 Icon
Effect: Reduces the length of hostile security alarms by 40 seconds.
Location: Bought at Gatherer's Garden.
Price: 50

Sports Boost[]

Sports Boost Effect: Slightly increases movement speed
Location: At the beginning of Ryan Amusements, under the sign "Memorial Museum", or bought at a Gatherer's Garden.
Price: 40

Thrifty Hacker[]

Thrifty Hacker Effect: Hacked vending prices are even cheaper.
Location: Obtained by researching Leadhead Splicers to the maximum level.
Price: N/A

Vending Expert[]

Clown
Effect: Provides a slight reduction to prices in vending machines.
Location: Downstairs in a flooded section of Siren Alley, or bought at a Gatherer's Garden.
Price: 75

Vending Expert 2[]

Vending Expert 2 Icon
Effect: Provides a substantial reduction to prices in vending machines.
Location: Reward for "following" the Unstable Teleportation Plasmid in Fontaine Futuristics, or bought at a Gatherer's Garden.
Price: 90

Walking Inferno[]

Walking Inferno (Bio 2) Effect: Boosts the effects of the user's fire-based attacks while providing a resistance to fire damage.
Location: Bought at Gatherer's Garden.
Price: 40

Minerva's Den Only[]

Main article: Minerva's Den

Drill Dash[]

Drill Dash Effect: Unlocks the Drill Dash ability when equipped.
Location: Found in the Security Bot showroom right after the entrance of McClendon Robotics, in Minerva's Den, or bought in Gatherer's Gardens.
Price: 75

Master Protector[]

Master Gatherer tonic Effect: Increases harvest times for any Little Sister the player's chaperoning, thereby increasing the amount of ADAM they collect by 40.
Location: Free at any Gatherer's Garden only if the player obtained all stars in the The Protector Trials.
Price: Free

Mentioned Gene Tonics[]

Animal Magnetism[]

Tonic Animal Magnetism
Effect: Increases the user's charisma and seductory prowess (if male).
Location: N/A
Price: Unknown

Anti-TB[]

Tonic Anti-TB
Effect: Immunizes the user against tuberculosis.
Location: N/A
Price: Unknown

Brain Boost[]

Tonic Brain Boost
Effect: Improves the user's thinking capabilities.
Location: N/A
Price: Unknown

Hemingway's Helper[]

N/A Effect: Cures writer's block and makes the user a better writer.
Location: N/A
Price: Unknown, but included with the Sinclair Solution's Tester Pack.

Slim-Down[]

Tonic Slim-Down
Effect: Sheds the user's excess fat.
Location: N/A
Price: Unknown

ReJuvena[]

ReJuvena
Effect: Tightens skin to reduce wrinkles.
Location: N/A
Price: Unknown

Removed Gene Tonics[]

EVE Auto Hack[]

TonicButton

Piercing Damage Over Time[]

TonicButton

Staggering Blow[]

TonicButton

Gatherer Harvest Bonus[]

TonicButton

Handyman 2[]

TonicButton

Freezing Drill 2[]

TonicButton

Medical Expert 2[]

TonicButton

Behind the Scenes[]

  • In BioShock 2's game files, there is a TonicBasicTraining video. When played, it plays a short version of the Enrage Plasmid's video, except "Tonics" is layered over the "Plasmids" at the start, and it seems to state it is a "PLACEHOLDER" for Tonic use videos. Considering this, one may assume the developers were planning on making the same Plasmid introductory videos for Tonics. This can be seen at Ryan Amusements on a screen in the Hall of The Future. There's no sound and the "Tonics by Ryan Industries" sign does not appear.
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