BioShock Wiki
BioShock Wiki

Andrew RyanHQ.jpg
"There is something more powerful than each of us, a combination of our efforts, a Great Chain of industry that unites us. But it is only when we struggle in our own interest that the chain pulls society in the right direction..."Andrew Ryan

This article falls within the scope of the BioShock Wiki:Businesses Project. This project is dedicated to improving the articles about Rapture and Columbia's many businesses.
Would you kindly help the BioShock Wiki by volunteering on the project page?
Peach Wilkins.jpg
"Come on in and show us those snappy snappies."Peach Wilkins

This article could use some more pictures. Would you kindly help BioShock Wiki by adding some?
Optimized Eugenics Logo.png

The entrance to Optimized Eugenics.

Here is where you be finding the voicebox to have sound like one of those Big Daddies. Repulsive creatures.
Brigid Tenenbaum[src]

Optimized Eugenics is the main research and testing facility of Point Prometheus in Rapture, dedicated to prototyping, analyzes and testing of new Plasmids and other genetic enhancements.


Fontaine Futuristics Door Point Prometheus.png
Fontaine Futuristics Point Prometheus.png

Optimized Eugenics was previously known as the Fontaine Futuristics Genetic Research Department before Andrew Ryan nationalized Fontaine Futuristics and eventually condemned their headquarters.[1] When the Civil War erupted, genetic research turned into an arms race with both sides looking for a way to get an edge in the conflict. Ryan Industries pushed its scientists into making more combat Plasmids, marketed as home-defense products. Point Prometheus became a strongpoint for the rebels led by Atlas, who took over the facility in the early weeks of the war. They were eventually driven out by Rapture's security forces.[2][3] At that time Plasmids went into shortage due to higher demand and limited ADAM generation.[4]

Optimized Eugenics had equipment for the development of new experimental Plasmids: analysis and prototyping rooms, a live testing area, storage for test subjects, and even a backup generator which would prevent any potential power shortage that might endanger the experiments and test subjects.



Main article: BioShock

In order to pursue Frank Fontaine through to the Proving Grounds, Jack must turn himself into a Big Daddy and trick a former Little Sister into opening the way. Optimized Eugenics holds the prototype voice modifier machine which will enable him to sound like one of the hulking Protectors.

Main Hall[]

The entrance to the facility is located on the upper floor of the main hall, opposite Failsafe Armored Escorts. A closet blocked by ice forming from a busted pipe is on the right, where the old signs and doors of the facility from the time of Fontaine Futuristics were hastily stashed away. A set of decontamination chambers are placed at the entrance, with the Security Monitoring Room in-between. The backup generator's temporary override switch and a Bot Shutdown Panel can be found in the security center.

Backup Generator[]

In the middle of the facility is a backup generator, ensuring power to the research labs and storage vats in case it failed in Point Prometheus. The floor is flooded and the generator emits electric arcs all around, making the place unsafe. The override switch in the Security Monitoring Room behind the area can temporary shut down the generator, allowing access to a safe guarded by a security camera.

Test Subject Storage[]

Test subject tanks.

On the South side of Optimized Eugenics are two large rooms each holding three vats filled with yellow, bubbling chemicals. This is where test subjects were stored before and after testing, their health status monitored by the scientists.

Eugenic Analysis[]

On the South-West corner is the Eugenic Analysis laboratory where samples from experiments were studied under industrial microscopes. The room holds a safe, guarded by two Turrets. There is also a Power to the People machine and a Gene Bank.

Plasmid Prototyping[]

The laboratory on the North-West corner holds two incubators and several consoles used to create and study experimental Plasmids before further testing. An RPG Turret guards the stairs to the elevated area.

Live Subject Testing[]

The Voicebox Modification Prototype.

On the North side of the facility is the testing area where experimental Plasmids and other genetic enhancements were injected in live test subjects immersed in large vats of yellow chemicals, one of them lying broken on the floor. A control room overlooks the vats, with several monitoring consoles to control the experiments, and a U-Invent machine. This is also where the Voicebox Modification Prototype 084 569-F is stored, a requirement to modify the larynx of candidates to the Protector Program and make their voice sound guttural.

New Discoveries[]

Single Use Events[]

  • There is one Power to the People station located next to the Gene Bank in Eugenics Analysis.

New Plasmids and Gene Tonics (Found)[]

  • Alarm Expert 2 - Live Subject Testing area, on a file cabinet near to the Voicebox Modification Prototype in the control room.

Audio Diaries[]

  1. Andrew Ryan - Marketing Gold - Optimized Eugenics, Test Subject Storage, on a machine against the wall.
  2. Dr. Suchong - Extra Munitions - Optimized Eugenics, Plasmid Prototyping, on the ground near RPG Turret.
  3. Dr. Suchong - Changing Employers - Frozen over doorway next to the entrance: melt the ice, enter the closet and search the trash can.


  1. Andrew Ryan's Audio Diary: Alone at Last
  2. Rapture Tribune headline in Burial at Sea - Episode 2: "Atlas' Parasites Driven from Point Prometheus"
  3. Civil War Announcement in Burial at Sea - Episode 2: "…Atlas' thugs have been pushed out of Point Prometheus, they're on the run in Port Neptune"
  4. Writing on a Rapture Tribune chalkboard: "Plasmid shortage loom as conflict continues"